Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition

Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition

3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol (HPN) is a bromophenol derivative from the marine red alga Rhodomela confervoides. We have previously found that HPN exerted an anti-hyperglycemic property in db/db mouse model. In the present study, we found that HPN co...

Full description

Bibliographic Details
Main Authors: Jiao Luo, Ning Wu, Bo Jiang, Lijun Wang, Shuaiyu Wang, Xiangqian Li, Baocheng Wang, Changhui Wang, Dayong Shi
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Marine Drugs
Subjects:
HPN
palmitate
PTP1B inhibition
anti-cell damage
anti-insulin resistance
HepG2 cell
Online Access:http://www.mdpi.com/1660-3397/13/7/4452

Internet

http://www.mdpi.com/1660-3397/13/7/4452

Similar Items