An in silico study of bioactive compounds of Annona muricata in the design of ani-prostate cancer agent: MM/GBSA, pharmacophore modeling and ADMET parameters

An in silico study of bioactive compounds of Annona muricata in the design of ani-prostate cancer agent: MM/GBSA, pharmacophore modeling and ADMET parameters

One of the most frequent diseases that affect and kill men globally is prostate cancer. Treatment for prostate cancer has become unpleasant and upsetting for individuals due to the resulting resistance, toxicity, and adverse effects of standard chemotherapies. Consequently, we report the identificat...

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Bibliographic Details
Main Authors: Victor Onukwube Apeh, Abayomi Emmanuel Adegboyega, Ifeoma Felicia Chukwuma, Chinenye Jane Ugwah-Oguejiofor, Patrick Maduabuchi Aja, Josephine Omose Ofeimun, Boniface Anthony Ale, Grace Inioluwa Johnson, Lilian Nwanneka Ebenyi, Opeyemi Iwaloye, Stephen Adakole Ejembi, Flora Nnenna Ezugworie, Titilayo Omolara Johnson
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Annona muricata
Prostate cancer
Pharmacophore modeling
In silico
Chemotherapies
Online Access:http://www.sciencedirect.com/science/article/pii/S235291482300223X

Internet

http://www.sciencedirect.com/science/article/pii/S235291482300223X

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