Naringin in the repair of knee cartilage injury via the TGF-β/ALK5/Smad2/3 signal transduction pathway combined with an acellular dermal matrix

Naringin in the repair of knee cartilage injury via the TGF-β/ALK5/Smad2/3 signal transduction pathway combined with an acellular dermal matrix

Objective: Based on the expression changes in the TGF-β/ALK5/Smad2/3 signal transduction pathway, the repair of cartilage injury in the rabbit knee joint was investigated and evaluated by oral administration of naringin in combination with acellular dermal matrix implantation. Methods: First, twenty...

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Bibliographic Details
Main Authors: Chao Ye, Jing Chen, Yi Qu, Hui Qi, Qingfu Wang, Zheng Yang, Aiming Wu, Fengxian Wang, Pengyang Li
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Naringin
Cartilage defect
Repair
Acellular dermal matrix
Transforming growth factor-β
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X21000498

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http://www.sciencedirect.com/science/article/pii/S2214031X21000498

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