The Thiol Group Reactivity and the Antioxidant Property of Human Serum Albumin Are Controlled by the Joint Action of Fatty Acids and Glucose Binding

The Thiol Group Reactivity and the Antioxidant Property of Human Serum Albumin Are Controlled by the Joint Action of Fatty Acids and Glucose Binding

The binding of ubiquitous serum ligands (free fatty acids) to human serum albumin (HSA) or its glycation can affect thiol group reactivity, thus influencing its antioxidant activity. The effects of stearic acid (SA) and glucose binding on HSA structural changes and thiol group content and reactivity...

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Bibliographic Details
Main Authors: Tamara Uzelac, Katarina Smiljanić, Marija Takić, Ivana Šarac, Gordana Oggiano, Milan Nikolić, Vesna Jovanović
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
antioxidant role
fatty acids
glucose
glycation
human serum albumin
thiol group content and reactivity
Online Access:https://www.mdpi.com/1422-0067/25/4/2335

Internet

https://www.mdpi.com/1422-0067/25/4/2335

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