Impact of inflammatory preconditioning on murine microglial proteome response induced by focal ischemic brain injury

Impact of inflammatory preconditioning on murine microglial proteome response induced by focal ischemic brain injury

Preconditioning with lipopolysaccharide (LPS) induces neuroprotection against subsequent cerebral ischemic injury, mainly involving innate immune pathways. Microglia are resident immune cells of the central nervous system (CNS) that respond early to danger signals through memory-like differential re...

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Bibliographic Details
Main Authors: Dario Lucas Helbing, Fabienne Haas, Emilio Cirri, Norman Rahnis, Therese Thuy Dung Dau, Erika Kelmer Sacramento, Nova Oraha, Leopold Böhm, Trim Lajqi, Pascal Fehringer, Helen Morrison, Reinhard Bauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
mice
inflammatory preconditioning
neuroinflammation
ischemic stroke
microglia
type I interferons
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1227355/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1227355/full

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