Duchenne Muscular Dystrophy from Brain to Muscle: The Role of Brain Dystrophin Isoforms in Motor Functions

Duchenne Muscular Dystrophy from Brain to Muscle: The Role of Brain Dystrophin Isoforms in Motor Functions

Brain function and its effect on motor performance in Duchenne muscular dystrophy (DMD) is an emerging concept. The present study explored how cumulative dystrophin isoform loss, age, and a corticosteroid treatment affect DMD motor outcomes. A total of 133 genetically confirmed DMD patients from Sri...

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Bibliographic Details
Main Authors: Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Dhammika Amaratunga, Yetrib Hathout, Chandra Mohan, Harry W. M. Steinbusch, Ashwin Dalal, Eric P. Hoffman, K. Ranil D. de Silva
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Journal of Clinical Medicine
Subjects:
muscular dystrophy
DMD
natural history
South Asia
genotype–phenotype
Online Access:https://www.mdpi.com/2077-0383/12/17/5637

Internet

https://www.mdpi.com/2077-0383/12/17/5637

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