The fat is in the lysosome: how Mycobacterium tuberculosis tricks macrophages into storing lipids

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), infects primarily macrophages, causing them to differentiate into lipid-laden foamy macrophages that are a primary source of tissue destruction in patients with TB. In this issue of the JCI, Bedard et al. demonstrate that 1-tuberc...

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Bibliographic Details
Main Authors: Yoann Rombouts, Olivier Neyrolles
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-03-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI168366