Neurogenic to Gliogenic Fate Transition Perturbed by Loss of HMGB2

Mouse cortical development relies heavily on a delicate balance between neurogenesis and gliogenesis. The lateral ventricular zone produces different classes of excitatory pyramidal cells until just before birth, when the production of astroglia begins to prevail. Epigenetic control of this fate shi...

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Bibliographic Details
Main Authors: Robert Bronstein, Jackson Kyle, Ariel B. Abraham, Stella E. Tsirka
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00153/full