A commentary on the inhibition of human TPC2 channel by the natural flavonoid naringenin: Methods, experiments, and ideas

Human endo-lysosomes possess a class of proteins called TPC channels on their membrane, which are essential for proper cell functioning. This protein family can be functionally studied by expressing them in plant vacuoles. Inhibition of hTPC activity by naringenin, one of the main flavonoids present...

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Bibliographic Details
Main Authors: Minicozzi Velia, Qi Tianwen, Gradogna Antonella, Pozzolini Marina, Milenkovic Stefan, Filippini Antonio, Ceccarelli Matteo, Carpaneto Armando
Format: Article
Language:English
Published: De Gruyter 2023-09-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc-2022-0036