Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators

Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators

Positive allosteric modulators (PAMs), negative allosteric modulators (NAMs), silent agonists, allosteric activating PAMs and neutral or silent allosteric modulators are compounds capable of modulating the nicotinic receptor by interacting at allosteric modulatory sites distinct from the orthosteric...

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Bibliographic Details
Main Authors: Dina Manetti, Silvia Dei, Hugo R. Arias, Laura Braconi, Alessio Gabellini, Elisabetta Teodori, Maria Novella Romanelli
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
positive allosteric modulator
negative allosteric modulator
desensitization
α7
α4β2
nicotinic acetylcholine receptor
Online Access:https://www.mdpi.com/1420-3049/28/3/1270

Internet

https://www.mdpi.com/1420-3049/28/3/1270

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