Impact of Liver Inflammation on Bile Acid Side Chain Shortening and Amidation

Impact of Liver Inflammation on Bile Acid Side Chain Shortening and Amidation

Bile acid (BA) synthesis from cholesterol by hepatocytes is inhibited by inflammatory cytokines. Whether liver inflammation also affects BA side chain shortening and conjugation was investigated. In human liver cell lines (IHH, HepG2, and HepaRG), agonists of nuclear receptors including the farnesoi...

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Bibliographic Details
Main Authors: Marta Alonso-Peña, Ricardo Espinosa-Escudero, Heike M. Hermanns, Oscar Briz, Jose M. Herranz, Carmen Garcia-Ruiz, Jose C. Fernandez-Checa, Javier Juamperez, Matias Avila, Josepmaria Argemi, Ramon Bataller, Javier Crespo, Maria J. Monte, Andreas Geier, Elisa Herraez, Jose J. G. Marin
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
ACOX2
ASH
BAAT
bile acid
inflammation
NAFL
Online Access:https://www.mdpi.com/2073-4409/11/24/3983

Internet

https://www.mdpi.com/2073-4409/11/24/3983

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