MR-spectroscopy in metachromatic leukodystrophy: A model free approach and clinical correlation

MR-spectroscopy in metachromatic leukodystrophy: A model free approach and clinical correlation

Background and purpose: Metachromatic leukodystrophy (MLD) is a lysosomal enzyme deficiency disorder leading to demyelination and subsequently to a progressive decline in cognitive and motor function. It affects mainly white matter where changes during the course of the disease can be visualized on...

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Bibliographic Details
Main Authors: Joana Feldmann, Pascal Martin, Benjamin Bender, Lucia Laugwitz, Laimdota Zizmare, Christoph Trautwein, Ingeborg Krägeloh-Mann, Uwe Klose, Samuel Groeschel
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:NeuroImage: Clinical
Subjects:
Metachromatic leukodystrophy
MR spectroscopy
NAA
N-acetylaspartate
Urine NMR spectroscopy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158222003618

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http://www.sciencedirect.com/science/article/pii/S2213158222003618

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