Influence of Process Parameters on Content Uniformity of a Low Dose Active Pharmaceutical Ingredient in a Tablet Formulation According to GMP

Influence of Process Parameters on Content Uniformity of a Low Dose Active Pharmaceutical Ingredient in a Tablet Formulation According to GMP

The article describes the development and production of tablets using direct compression of powder mixtures. The aim was to describe the impact of filler particle size and the time of lubricant addition during mixing on content uniformity according to the Good Manufacturing Practice (GMP) process va...

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Bibliographic Details
Main Authors: Muselík Jan, Franc Aleš, Doležel Petr, Goněc Roman, Krondlová Anna, Lukášová Ivana
Format: Article
Language:English
Published: Sciendo 2014-09-01
Series:Acta Pharmaceutica
Subjects:
content uniformity
warfarin
validation
narrow therapeutic index
faraday pail
pls regression
Online Access:https://doi.org/10.2478/acph-2014-0022

Internet

https://doi.org/10.2478/acph-2014-0022

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