Effects of pH alteration on respiratory syncytial virus in human airway epithelial cells

Background Respiratory syncytial virus (RSV) is a leading cause of respiratory distress and hospitalisation in the paediatric population. Low airway surface pH impairs antimicrobial host defence and worsens airway inflammation. Inhaled Optate safely raises airway surface pH in humans and raises intr...

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Bibliographic Details
Main Authors: Jessica L. Saunders, Ivana A. Daniels, Taiya L. Edwards, Ryan F. Relich, Yi Zhao, Laura A. Smith, Benjamin M. Gaston, Michael D. Davis
Format: Article
Language:English
Published: European Respiratory Society 2023-07-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/9/4/00404-2022.full