Microwave-assisted synthesis and pharmacological screening of some triazolothiadiazole derivatives

In this study, twenty-two new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles (5a-n, 6a-h) were synthesized under microwave irradiation (MWI). The chemical structures of the compounds were elucidated by their IR, 1H-NMR, LC-MS, and elemental analysis. The compounds were tested for antinociceptive activity...

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Bibliographic Details
Main Authors: Ozge Gorgu, Engin Yıldırım, Yesim Ozkan, Bilge Cakır, Kevser Erol, Tijen Onkol
Format: Article
Language:English
Published: Universidade de São Paulo 2020-03-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100526&tlng=en