Senescent fibroblast facilitates re-epithelization and collagen deposition in radiation-induced skin injury through IL-33-mediated macrophage polarization

Senescent fibroblast facilitates re-epithelization and collagen deposition in radiation-induced skin injury through IL-33-mediated macrophage polarization

Abstract Background The need for radiotherapy among the elderly rises with increasing life expectancy and a corresponding increase of elderly cancer patients. Radiation-induced skin injury is one of the most frequent adverse effects in radiotherapy patients, severely limiting their life quality. Re-...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Yan Chen, Le Ma, Zhuo Cheng, Zhihe Hu, Yang Xu, Jie Wu, Yali Dai, Chunmeng Shi
Format: Artykuł
Język:English
Wydane: BMC 2024-02-01
Seria:Journal of Translational Medicine
Hasła przedmiotowe:
Senescence
IL-33
Macrophages
Radiation-induced skin injury
Dostęp online:https://doi.org/10.1186/s12967-024-04972-8

Internet

https://doi.org/10.1186/s12967-024-04972-8

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