Nevirapine induced mitochondrial dysfunction in HepG2 cells

Abstract Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor frequently used in combination with other antiretroviral agents for highly active antiretroviral therapy (HAART) of patients infected with the human immunodeficiency virus type 1 (HIV-1). However NVP can cause serious, lif...

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Bibliographic Details
Main Authors: Atchara Paemanee, Wannapa Sornjai, Suthathip Kittisenachai, Naraporn Sirinonthanawech, Sittiruk Roytrakul, Jeerang Wongtrakul, Duncan R. Smith
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09321-y