T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens
T lymphocytes’ ability to discriminate between structurally related antigens has been attributed to the unique signaling properties of the T cell receptor. However, recent studies have suggested that the output of this discrimination process is conditioned by environmental cues. Here, we demonstrate...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-05-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715004684 |