Superenhancers as master gene regulators and novel therapeutic targets in brain tumors

Brain cancer: opportunities to block “super-enhanced” tumor growth “Superenhancer” regions within the genome help coordinate the malignant growth of brain tumors, and could offer a target for the development of therapies and prognostic biomarkers. These regions contain a dense accumulation of gene r...

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Bibliographic Details
Main Authors: Hai-Hui Zhuang, Qiang Qu, Xin-Qi Teng, Ying-Huan Dai, Jian Qu
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00934-0