Novel Antiplatelet Activity of Minocycline Involves Inhibition of MLK3-p38 Mitogen Activated Protein Kinase Axis.

Novel Antiplatelet Activity of Minocycline Involves Inhibition of MLK3-p38 Mitogen Activated Protein Kinase Axis.

Platelets play an essential role in hemostasis and wound healing by facilitating thrombus formation at sites of injury. Platelets also mediate inflammation and contain several pro-inflammatory molecules including cytokines and chemokines that mediate leukocyte recruitment and activation. Not surpris...

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Bibliographic Details
Main Authors: Joseph W Jackson, Meera V Singh, Vir B Singh, Letitia D Jones, Gregory A Davidson, Sara Ture, Craig N Morrell, Giovanni Schifitto, Sanjay B Maggirwar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4894566?pdf=render

Internet

http://europepmc.org/articles/PMC4894566?pdf=render

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