Quantifying the impact of inter-site heterogeneity on the distribution of ChIP-seq data

Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a valuable tool for epigenetic studies. Analysis of the data arising from ChIP-seq experiments often requires implicit or explicit statistical modelling of the read counts. The simple Poisson model is attractive, but does not provide...

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Bibliographic Details
Main Authors: Jonathan eCairns, Andy G Lynch, Simon eTavaré
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00399/full