Requirement of retinoic acid receptor β for genipin derivative-induced optic nerve regeneration in adult rat retina.

Like other CNS neurons, mature retinal ganglion cells (RGCs) are unable to regenerate their axons after nerve injury due to a diminished intrinsic regenerative capacity. One of the reasons why they lose the capacity for axon regeneration seems to be associated with a dramatic shift in RGCs' pro...

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Bibliographic Details
Main Authors: Yoshiki Koriyama, Yusuke Takagi, Kenzo Chiba, Matsumi Yamazaki, Kayo Sugitani, Kunizo Arai, Hirokazu Suzuki, Satoru Kato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3735487?pdf=render