L-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction.

L-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction.

Transforming growth factor-β (TGF-β) plays a pivotal role in renal fibrosis. Endoglin, a 180 KDa membrane glycoprotein, is a TGF-β co-receptor overexpressed in several models of chronic kidney disease, but its function in renal fibrosis remains uncertain. Two membrane isoforms generated by alternati...

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Bibliographic Details
Main Authors: Bárbara Oujo, José M Muñoz-Félix, Miguel Arévalo, Elena Núñez-Gómez, Lucía Pérez-Roque, Miguel Pericacho, María González-Núñez, Carmen Langa, Carlos Martínez-Salgado, Fernando Perez-Barriocanal, Carmelo Bernabeu, José M Lopez-Novoa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4196986?pdf=render

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http://europepmc.org/articles/PMC4196986?pdf=render

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