Neglected SARS-CoV-2 variants and potential concerns for molecular diagnostics: a framework for nucleic acid amplification test target site quality assurance

Neglected SARS-CoV-2 variants and potential concerns for molecular diagnostics: a framework for nucleic acid amplification test target site quality assurance

ABSTRACT During the COVID-19 pandemic, SARS-CoV-2 detection using nucleic acid amplification tests (NAATs) played a key role in clinical management and public health interventions. However, mutations could jeopardize NAAT-based detection if they occur in the NAAT target site, potentially resulting i...

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Bibliographic Details
Main Authors: Gregory R. McCracken, Daniel Gaston, Janice Pettipas, Allana Loder, Anna Majer, Elsie Grudeski, Geneviève Labbé, Bryn K. Joy, Glenn Patriquin, Jason J. LeBlanc
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
quality
COVID-19
SARS-CoV-2
PCR
mutation
NAAT
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00761-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.00761-23

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