Acute Promyelocytic Leukemia (APL): A Review of the Classic and Emerging Target Therapies towards Molecular Heterogeneity

The occurrence of severe bleeding syndrome because of the PML-RARα fusion protein is a life-threatening event in APL. This protein destabilizes homeostasis, maturation, remodeling, and tissue regeneration in addition to hampering the maintenance and differentiation of hematopoietic cells into differ...

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Bibliographic Details
Main Authors: Tâmara Dauare de Almeida, Fernanda Cristina Gontijo Evangelista, Adriano de Paula Sabino
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Future Pharmacology
Subjects:
Online Access:https://www.mdpi.com/2673-9879/3/1/12