Effects of tDCS on Brain Functional Network of Patients After Stroke

Transcranial direct current stimulation (tDCS) is an emerging brain intervention technique. However, the effects of tDCS on stroke patients are unclear. In this study, Granger Causality (GC) is used to construct brain functional networks of the tDCS group (9 cases) and the sham tDCS group (11 cases)...

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Main Authors: Hongli Wang, Hongli Yu, Mengmeng Liu, Guizhi Xu, Lei Guo, Chunfang Wang, Changcheng Sun
Format: Article
Language:English
Published: IEEE 2020-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/9258949/
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author Hongli Wang
Hongli Yu
Mengmeng Liu
Guizhi Xu
Lei Guo
Chunfang Wang
Changcheng Sun
author_facet Hongli Wang
Hongli Yu
Mengmeng Liu
Guizhi Xu
Lei Guo
Chunfang Wang
Changcheng Sun
author_sort Hongli Wang
collection DOAJ
description Transcranial direct current stimulation (tDCS) is an emerging brain intervention technique. However, the effects of tDCS on stroke patients are unclear. In this study, Granger Causality (GC) is used to construct brain functional networks of the tDCS group (9 cases) and the sham tDCS group (11 cases). Some parameters of brain functional networks are analyzed comparatively, such as degree, clustering coefficient, betweenness centrality, characteristic path length, and efficiency. In tDCS group, the results show that the distribution of degree changes greatly in left prefrontal lobe and left temporal lobe regions, the distribution of betweenness centrality transfers, characteristic path length decreases, clustering coefficient and efficiency increase significantly (p<; 0.05) after stimulation. However, there is no significant difference in sham tDCS group. In this study, the positive effects of tDCS on the therapeutic of stroke are clarified and the evidence for the effects of tDCS on stroke is provided.
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spelling doaj.art-afc468d8e6b34d899931c1c11277c3842022-12-21T19:59:38ZengIEEEIEEE Access2169-35362020-01-01820562520563410.1109/ACCESS.2020.30379249258949Effects of tDCS on Brain Functional Network of Patients After StrokeHongli Wang0https://orcid.org/0000-0002-6219-9436Hongli Yu1https://orcid.org/0000-0002-8487-5079Mengmeng Liu2https://orcid.org/0000-0002-7072-3218Guizhi Xu3https://orcid.org/0000-0002-9637-0051Lei Guo4https://orcid.org/0000-0003-3427-8222Chunfang Wang5https://orcid.org/0000-0001-6201-3980Changcheng Sun6https://orcid.org/0000-0001-5637-6662State Key Laboratory of Reliable and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, ChinaState Key Laboratory of Reliable and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, ChinaState Key Laboratory of Reliable and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, ChinaState Key Laboratory of Reliable and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, ChinaState Key Laboratory of Reliable and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, ChinaRehabilitation Department, Tianjin Union Medical Centre, Tianjin, ChinaRehabilitation Department, Tianjin Union Medical Centre, Tianjin, ChinaTranscranial direct current stimulation (tDCS) is an emerging brain intervention technique. However, the effects of tDCS on stroke patients are unclear. In this study, Granger Causality (GC) is used to construct brain functional networks of the tDCS group (9 cases) and the sham tDCS group (11 cases). Some parameters of brain functional networks are analyzed comparatively, such as degree, clustering coefficient, betweenness centrality, characteristic path length, and efficiency. In tDCS group, the results show that the distribution of degree changes greatly in left prefrontal lobe and left temporal lobe regions, the distribution of betweenness centrality transfers, characteristic path length decreases, clustering coefficient and efficiency increase significantly (p<; 0.05) after stimulation. However, there is no significant difference in sham tDCS group. In this study, the positive effects of tDCS on the therapeutic of stroke are clarified and the evidence for the effects of tDCS on stroke is provided.https://ieeexplore.ieee.org/document/9258949/Transcranial direct current stimulation (tDCS)brain functional networkstrokeelectroencephalogram (EEG)
spellingShingle Hongli Wang
Hongli Yu
Mengmeng Liu
Guizhi Xu
Lei Guo
Chunfang Wang
Changcheng Sun
Effects of tDCS on Brain Functional Network of Patients After Stroke
IEEE Access
Transcranial direct current stimulation (tDCS)
brain functional network
stroke
electroencephalogram (EEG)
title Effects of tDCS on Brain Functional Network of Patients After Stroke
title_full Effects of tDCS on Brain Functional Network of Patients After Stroke
title_fullStr Effects of tDCS on Brain Functional Network of Patients After Stroke
title_full_unstemmed Effects of tDCS on Brain Functional Network of Patients After Stroke
title_short Effects of tDCS on Brain Functional Network of Patients After Stroke
title_sort effects of tdcs on brain functional network of patients after stroke
topic Transcranial direct current stimulation (tDCS)
brain functional network
stroke
electroencephalogram (EEG)
url https://ieeexplore.ieee.org/document/9258949/
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