Effects of Oral Cannabinoids on Systemic Inflammation and Viral Reservoir Markers in People with HIV on Antiretroviral Therapy: Results of the CTN PT028 Pilot Clinical Trial

Effects of Oral Cannabinoids on Systemic Inflammation and Viral Reservoir Markers in People with HIV on Antiretroviral Therapy: Results of the CTN PT028 Pilot Clinical Trial

Chronic HIV infection is characterized by persistent inflammation despite antiretroviral therapy (ART). Cannabinoids may help reduce systemic inflammation in people with HIV (PWH). To assess the effects of oral cannabinoids during HIV, ten PWH on ART were randomized (<i>n</i> = 5/group)...

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Bibliographic Details
Main Authors: Ralph-Sydney Mboumba Bouassa, Eve Comeau, Yulia Alexandrova, Amélie Pagliuzza, Alexis Yero, Suzanne Samarani, Judy Needham, Joel Singer, Terry Lee, Florian Bobeuf, Claude Vertzagias, Giada Sebastiani, Shari Margolese, Enrico Mandarino, Marina B. Klein, Bertrand Lebouché, Jean-Pierre Routy, Nicolas Chomont, Cecilia T. Costiniuk, Mohammad-Ali Jenabian
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
cannabinoids
Δ9-tetrahydrocannabinol (THC)
cannabidiol (CBD)
systemic inflammation
immune response
HIV reservoir
Online Access:https://www.mdpi.com/2073-4409/12/14/1811

Internet

https://www.mdpi.com/2073-4409/12/14/1811

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