Asymmetric Synthesis of Enantiomerically Pure Aliphatic and Aromatic D-Amino Acids Catalyzed by Transaminase from <i>Haliscomenobacter hydrossis</i>

Asymmetric Synthesis of Enantiomerically Pure Aliphatic and Aromatic D-Amino Acids Catalyzed by Transaminase from <i>Haliscomenobacter hydrossis</i>

D-amino acids are valuable building blocks for the synthesis of biologically active compounds and pharmaceuticals. The asymmetric synthesis of chiral amino acids from prochiral ketones using stereoselective enzymes is a well-known but far from exhausted approach for large-scale production. Herein, w...

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Bibliographic Details
Main Authors: Alina K. Bakunova, Tatiana Y. Isaikina, Vladimir O. Popov, Ekaterina Yu. Bezsudnova
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Catalysts
Subjects:
D-amino acid transaminase
substrate specificity
synthesis of D-amino acids
stereoselective amination of keto acids
PLP leakage
Online Access:https://www.mdpi.com/2073-4344/12/12/1551

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https://www.mdpi.com/2073-4344/12/12/1551

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