Case report: Effectiveness of sirolimus in treating partial DiGeorge Syndrome with Autoimmune Lymphoproliferative Syndrome (ALPS)-like features

Case report: Effectiveness of sirolimus in treating partial DiGeorge Syndrome with Autoimmune Lymphoproliferative Syndrome (ALPS)-like features

BackgroundDiGeorge Syndrome (DGS) is a rare disease associated with 22q11.2 chromosomal microdeletion, also known as a velocardiofacial syndrome, based on the frequent involvements of the palate, facial, and heart problems. Hematologic autoimmunity is rare in DGS but presents with a refractory cours...

Full description

Bibliographic Details
Main Authors: Hao Gu, Wenjun Mou, Zhenping Chen, Xingjuan Xie, Jiafeng Yao, Rui Zhang, Runhui Wu, Jingang Gui
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pediatrics
Subjects:
DiGeorge syndrome
ALPS-like
DNTs
mTOR
sirolimus monotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.1014249/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2022.1014249/full

Similar Items