Hemopexin alleviates cognitive dysfunction after focal cerebral ischemia-reperfusion injury in rats
Abstract Background Ischemia-reperfusion (I/R) is a critical pathophysiological basis of cognitive dysfunction caused by ischemia stroke. Heme-oxygenase-1 (HO-1) is the rate-limiting enzyme for the elimination of excessive free heme by combining with hemopexin (HPX), a plasma protein that contribute...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-01-01
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Series: | BMC Anesthesiology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12871-019-0681-2 |