Physiopathological mechanisms underlying Alzheimer’s disease: a narrative review
ABSTRACT The neuropathological signature of Alzheimer’s disease (AD) comprises mainly amyloid plaques, and neurofibrillary tangles, resulting in synaptic and neuronal loss. These pathological structures stem from amyloid dysfunctional metabolism according to the amyloid cascade hypothesis, leading t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Associação Neurologia Cognitiva e do Comportamento
2024-12-01
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| Series: | Dementia & Neuropsychologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642024000100216&lng=en&tlng=en |