Polysaccharide from Atractylodes macrocephala Koidz. ameliorates DSS-induced colitis in mice by regulating the Th17/Treg cell balance

Polysaccharide from Atractylodes macrocephala Koidz. ameliorates DSS-induced colitis in mice by regulating the Th17/Treg cell balance

Atractylodes macrocephala Koidz. is one of the most frequently used traditional Chinese medicines for the treatment of ulcerative colitis (UC). The beneficial effect of polysaccharide from Atractylodes macrocephala Koidz. (PAMK) on UC has been reported, while the underlying mechanism and target rema...

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Bibliographic Details
Main Authors: Mengjiao Yang, Qianwen Zhang, Reham Taha, Mohammed Ismail Abdelmotalab, Qing Wen, Yuzhu Yuan, Yongrui Zhao, Qingyu Li, Chunyu Liao, Xin Huang, Zhenzhou Jiang, Chenghan Chu, Chunhua Jiao, Lixin Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
polysaccharide from Atractylodes macrocephala Koidz.
ulcerative colitis
transcriptional profile
Th17/Treg cell balance
IL-6/STAT3
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1021695/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1021695/full

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