Discovery–Versus Hypothesis–Driven Detection of Protein–Protein Interactions and Complexes

Discovery–Versus Hypothesis–Driven Detection of Protein–Protein Interactions and Complexes

Protein complexes are the main functional modules in the cell that coordinate and perform the vast majority of molecular functions. The main approaches to identify and quantify the interactome to date are based on mass spectrometry (MS). Here I summarize the benefits and limitations of different MS-...

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Bibliographic Details
Main Author: Isabell Bludau
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
protein complexes
protein-protein interactions
interactomics
mass-spectrometry
targeted proteomics
data analysis
Online Access:https://www.mdpi.com/1422-0067/22/9/4450

Internet

https://www.mdpi.com/1422-0067/22/9/4450

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