Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira

Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic Leptospira

Leptospirosis is an emerging zoonotic disease with more than 1 million cases annually. Currently there is lack of evidence for signaling pathways involved during the infection process of Leptospira. In our comprehensive genomic analysis of 20 Leptospira spp. we identified seven pathogen-specific Two...

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Bibliographic Details
Main Authors: Haritha Adhikarla, Elsio A. Wunder, Ariel E. Mechaly, Sameet Mehta, Zheng Wang, Luciane Santos, Vimla Bisht, Peter Diggle, Gerald Murray, Ben Adler, Francesc Lopez, Jeffrey P. Townsend, Eduardo Groisman, Mathieu Picardeau, Alejandro Buschiazzo, Albert I. Ko
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Leptospira
pathogenic
branched signaling
two-component system
hybrid histidine kinase
hybrid response regulator
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00045/full

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http://journal.frontiersin.org/article/10.3389/fcimb.2018.00045/full

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