U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing

U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing

RNA viruses quickly evolve subtle genotypic changes that can have major impacts on viral fitness and host range, with potential consequences for human health. It is therefore important to understand the evolutionary fitness of novel viral variants relative to well-studied genotypes of epidemic virus...

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Bibliographic Details
Main Authors: Jennifer Diaz, John Sears, Che-Kang Chang, Jane Burdick, Isabella Law, Wes Sanders, Colton Linnertz, Paul Sylvester, Nathaniel Moorman, Martin T. Ferris, Mark T. Heise
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Viruses
Subjects:
competition assay
nanopore sequencing
alphavirus
RNA virus
viral fitness
Online Access:https://www.mdpi.com/1999-4915/16/4/636

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https://www.mdpi.com/1999-4915/16/4/636

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