Computational integration of homolog and pathway gene module expression reveals general stemness signatures.

The stemness hypothesis states that all stem cells use common mechanisms to regulate self-renewal and multi-lineage potential. However, gene expression meta-analyses at the single gene level have failed to identify a significant number of genes selectively expressed by a broad range of stem cell typ...

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Bibliographic Details
Main Authors: Martina Koeva, E Camilla Forsberg, Joshua M Stuart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084730?pdf=render