Cartilage type IIB procollagen NH2-propeptide, PIIBNP, inhibits angiogenesis

Cartilage tissue is avascular and resistant to tumor invasion, but the basis for these properties is still unclear. Here we report that the NH2-propeptide of type IIB procollagen (PIIBNP), a product of collagen biosynthesis, is capable of inhibiting angiogenesis both in vitro and in vivo. PIIBNP inh...

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Bibliographic Details
Main Authors: Zhepeng Wang, Aiwu Lu
Format: Article
Language:English
Published: AIMS Press 2021-12-01
Series:AIMS Molecular Science
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/molsci.2021022?viewType=HTML