Oncogenic herpesvirus KSHV Hijacks BMP-Smad1-Id signaling to promote tumorigenesis.

Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma (KS), a malignancy commonly found in AIDS patients. Whether KS is a true neoplasm or hyperplasia has been a subject of intensive debate until recently when KSHV is unequivocally shown to efficiently...

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Bibliographic Details
Main Authors: Deguang Liang, Hao Hu, Shasha Li, Jiazhen Dong, Xing Wang, Yuhan Wang, Li He, Zhiheng He, Yuan Gao, Shou-Jiang Gao, Ke Lan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4092152?pdf=render