Low antithrombin levels are associated with low risk of cardiovascular death but are a risk factor for cancer mortality

<h4>Background</h4> Thrombosis is common in subjects suffering from cardiovascular diseases (CVD) and cancer. Hypercoagulation plays a pivotal role in the pathophysiology of thrombosis. Therefore, the inactivation of thrombin, the key enzyme in coagulation, is tightly regulated via antit...

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Main Authors: Licia Iacoviello, Romy de Laat-Kremers, Simona Costanzo, Qiuting Yan, Augusto Di Castelnuovo, Lisa van der Vorm, Amalia De Curtis, Marisa Ninivaggi, Chiara Cerletti, Maria Benedetta Donati, Bas de Laat, on behalf of the Moli-sani Investigators
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484666/?tool=EBI