Circular RNA circPOSTN promotes neovascularization by regulating miR-219a-2-3p/STC1 axis and stimulating the secretion of VEGFA in glioblastoma

Abstract Glioblastoma (GBM), the most malignant type of astrocytic tumor, is one of the deadliest cancers prevalent in adults. Along with tumor growth, patients with GBM generally suffer from extensive cerebral edema and apparent symptoms of intracranial hyper-pressure. Accumulating evidence has dem...

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Bibliographic Details
Main Authors: Niya Long, Xu Xu, Hongyi Lin, Ying Lv, Shenghui Zou, Han Cao, Xueshu Chen, Yan Zhao, Xiaolan Qi, Hua Yang, Jian Liu, Liangzhao Chu
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01136-9