CXCL1 Regulated by miR-302e Is Involved in Cell Viability and Motility of Colorectal Cancer via Inhibiting JAK-STAT Signaling Pathway

CXCL1 Regulated by miR-302e Is Involved in Cell Viability and Motility of Colorectal Cancer via Inhibiting JAK-STAT Signaling Pathway

PurposeThis study made a systemic description for the CXCL1-dependent regulatory mechanism in colorectal cancer (CRC).MethodsBioinformatics methods were applied to obtain target mRNA CXCL1 and corresponding upstream miRNA. qRT-PCR and Western blot were performed to measure the levels of CXCL1 and mi...

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Bibliographic Details
Main Authors: Biyin Chen, Li Song, Xiuzhen Nie, Fangfeng Lin, Zongyang Yu, Wencui Kong, Xiaoyan Qi, Wenwu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
miR-302e
chemokine ligand-1
janus kinase signal transducer and activator of transcription
colorectal cancer
proliferation
migration and invasion
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.577229/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.577229/full

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