Klebsiella quasipneumoniae in intestine damages bile acid metabolism in hematopoietic stem cell transplantation patients with bloodstream infection

Klebsiella quasipneumoniae in intestine damages bile acid metabolism in hematopoietic stem cell transplantation patients with bloodstream infection

Abstract Background Bloodstream infection (BSI) is a serious hematopoietic stem cell transplantation (HSCT) complication. The intestinal microbiome regulates host metabolism and maintains intestinal homeostasis. Thus, the impact of microbiome on HSCT patients with BSI is essential. Methods Stool and...

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Bibliographic Details
Main Authors: Guankun Yin, Yifan Guo, Qi Ding, Shuai Ma, Fengning Chen, Qi Wang, Hongbin Chen, Hui Wang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Translational Medicine
Subjects:
Hematopoietic stem cell transplantation
Bloodstream infection
Intestinal microbiome
Klebsiella quasipneumonae
Serum metabolome
Primary bile acid
Online Access:https://doi.org/10.1186/s12967-023-04068-9

Internet

https://doi.org/10.1186/s12967-023-04068-9

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