Chondrocyte Hypertrophy in Osteoarthritis: Mechanistic Studies and Models for the Identification of New Therapeutic Strategies

Chondrocyte Hypertrophy in Osteoarthritis: Mechanistic Studies and Models for the Identification of New Therapeutic Strategies

Articular cartilage shows limited self-healing ability owing to its low cellularity and avascularity. Untreated cartilage defects display an increased propensity to degenerate, leading to osteoarthritis (OA). During OA progression, articular chondrocytes are subjected to significant alterations in g...

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Bibliographic Details
Main Authors: Shikha Chawla, Andrea Mainardi, Nilotpal Majumder, Laura Dönges, Bhupendra Kumar, Paola Occhetta, Ivan Martin, Christian Egloff, Sourabh Ghosh, Amitabha Bandyopadhyay, Andrea Barbero
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
osteoarthritis
cartilage
hypertrophy
signaling pathway
Online Access:https://www.mdpi.com/2073-4409/11/24/4034

Internet

https://www.mdpi.com/2073-4409/11/24/4034

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