IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike

IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike

The secreted enzyme interleukin four-induced gene 1 (IL4I1) is involved in the negative control of the adaptive immune response. IL4I1 expression in human cancer is frequent and correlates with poor survival and resistance to immunotherapy. Nevertheless, its mechanism of action remains partially unk...

Full description

Bibliographic Details
Main Authors: Jérôme Gatineau, Charlotte Nidercorne, Aurélie Dupont, Marie-Line Puiffe, José L. Cohen, Valérie Molinier-Frenkel, Florence Niedergang, Flavia Castellano
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
IL4I1
immunosuppressive enzymes
SARS-CoV-2
spike
cancer therapy
moonlighting protein
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.982839/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.982839/full

Similar Items