SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1

SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1

Objective: Brown adipose tissue (BAT) is important for thermoregulation in many mammals. Uncoupling protein 1 (UCP1) is the critical regulator of thermogenesis in BAT. Here we aimed to investigate the deacetylation control of BAT and to investigate a possible functional connection between UCP1 and s...

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Bibliographic Details
Main Authors: Rajaa Sebaa, Jeff Johnson, Chantal Pileggi, Michaela Norgren, Jian Xuan, Yuka Sai, Qiang Tong, Izabella Krystkowiak, Emma Bondy-Chorney, Norman E. Davey, Nevan Krogan, Michael Downey, Mary-Ellen Harper
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S221287781830958X

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http://www.sciencedirect.com/science/article/pii/S221287781830958X

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