Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis

Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis

Abstract Background Sevoflurane is considered as a lung-protective factor in acute lung injury (ALI), but the underlying molecular mechanism remains largely unknown. The present study identified for the first time that sevoflurane ameliorated lipopolysaccharide (LPS)-induced ALI through regulating a...

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Bibliographic Details
Main Authors: Zhiling Fu, Xiuying Wu, Fushuang Zheng, Yan Zhang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Pulmonary Medicine
Subjects:
Acute lung injury
Sevoflurane
LINC00839
miR-223
NLRP3
Pyroptosis
Online Access:https://doi.org/10.1186/s12890-022-01957-5

Internet

https://doi.org/10.1186/s12890-022-01957-5

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