Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway

Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway

Background: Pulmonary fibrosis (PF) is a terminal pathological change in a variety of lung diseases characterized by excessive deposition of extracellular matrix, for which effective treatment is lacking. Tangeretin (Tan), a flavonoid derived from citrus, has been shown to have a wide range of pharm...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Jiang Li, Qian Wei, Ke Song, Youxin Wang, Yuxin Yang, Miao Li, Jiaying Yu, Guangxu Su, Luyuan Peng, Bendong Fu, Pengfei Yi
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Frontiers Media S.A. 2023-09-01
Sraith:Frontiers in Pharmacology
Ábhair:
pulmonary fibrosis
tangeretin
PI3K/Akt signaling pathway
epithelial-mesenchymal transition
bleomycin
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fphar.2023.1247800/full

Ar líne

https://www.frontiersin.org/articles/10.3389/fphar.2023.1247800/full

Míreanna comhchosúla