Plasma Assay of Cell-Free Methylated DNA Markers of Colorectal Cancer: A Tumor-Agnostic Approach to Monitor Recurrence and Response to Anticancer Therapies

Plasma Assay of Cell-Free Methylated DNA Markers of Colorectal Cancer: A Tumor-Agnostic Approach to Monitor Recurrence and Response to Anticancer Therapies

Background: Radiographic surveillance of colorectal cancer (CRC) after curative-intent therapy is costly and unreliable. Methylated DNA markers (MDMs) detected primary CRC and metastatic recurrence with high sensitivity and specificity in cross-sectional studies. This study evaluated using serial MD...

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Bibliographic Details
Main Authors: Mojun Zhu, William R. Taylor, Douglas W. Mahoney, Sara S. Then, Calise K. Berger, Kelli N. Burger, Anna M. Gonser, Karen A. Doering, Hao Xie, Patrick H. Foote, Michael W. Kaiser, Hatim T. Allawi, Joleen M. Hubbard, John B. Kisiel
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
liquid biopsy
neoplasm
residual
DNA methylation
colorectal neoplasms/therapy
Online Access:https://www.mdpi.com/2072-6694/15/24/5778

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https://www.mdpi.com/2072-6694/15/24/5778

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