CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles

CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles

Activation of voltage-gated calcium channels at presynaptic terminals leads to local increases in calcium and the fusion of synaptic vesicles containing neurotransmitter. Presynaptic output is a function of the density of calcium channels, the dynamic properties of the channel, the distance to docke...

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Bibliographic Details
Main Authors: Brian D Mueller, Sean A Merrill, Shigeki Watanabe, Ping Liu, Longgang Niu, Anish Singh, Pablo Maldonado-Catala, Alex Cherry, Matthew S Rich, Malan Silva, Andres Villu Maricq, Zhao-Wen Wang, Erik M Jorgensen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
L-type
N-type
super-resolution microscopy
Munc13
calcium channels
ryanodine receptor
Online Access:https://elifesciences.org/articles/81407

Internet

https://elifesciences.org/articles/81407

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