JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation

AP-1 family transcription factors regulate CD4+ T helper cell differentiation. Here the authors show that the AP-1 member JunB is a nonredundant regulator of transcriptional programs that support Th17 cell identity and restrain alternative Th1 and Treg cell fates in inflammatory contexts of acute fu...

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Bibliographic Details
Main Authors: Tiffany M. Carr, Joshua D. Wheaton, Geoffrey M. Houtz, Maria Ciofani
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00380-3